Research interests

  • Industrial scale bioprocessing and scale up/scale down
  • Smart bioproduction grids / biorefinery concepts
  • Bio-process analytical technology
  • High throughput bioprocess development by automation, mathematical modeling, machine learning
  • Microbial molecular genetics and biocatalysis

Research Units in UniSysCat

Awards (selection)

2023 Agilent Thought Leader Award
2020 selection of the KIWI-biolab ( as one of three “International Future Labs for Artificial Intelligence” of the German Federal Ministry of Education and Research (BMBF)
2014 Visiting Research Professor at the University of Oulu, Finland
2010 Visiting Research Professor at the CSIR, Pretoria, South Africa
2006 Research scholarship from the Alfried Krupp von Bohlen und Halbach Foundation's Collegiate Program “Life sciences – Medicine, Life and Health sciences”

UniSysCat Publications

Fan, Q., Caserta, G., Lorent, C., Lenz, O., Neubauer, P., Gimpel, M., Optimization of Culture Conditions for Oxygen-Tolerant Regulatory [NiFe]-Hydrogenase Production from Ralstonia eutropha H16 in Escherichia coli. Microorganisms. 2021, 9(6),1195.

Fan, Q., Neubauer, P., Lenz, O., Gimpel, M., Heterologous Hydrogenase Overproduction Systems for Biotechnology—An Overview, International Journal of Molecular Sciences, 2020, 21, 5890–0.

Schipp, C. J., Ma, Y., Al-Shameri, A., D'Alessio, F., Neubauer, P., Contestabile, R., Budisa, N., di Salvo, M. L., An Engineered Escherichia coli Strain with Synthetic Metabolism for In‐cell Production of Translationally Active Methionine Derivatives, ChemBioChem, 2020, 21, 3525.

Kaspar, F., Giessmann, R. T., Westarp, S., Helendahl, K. F., Krausch, N., Thiele, I., Walczak, M. C., Neubauer, P., Wagner, A., Spectral Unmixing-Based Reaction Monitoring of Transformations between Nucleosides and Nucleobases. ChemBioChem, 2020, 21(18), 2604-2610.

Ongey, E. L., Giessmann, R. T., Fons, M., Rappsilber, J., Adrian, L., Neubauer, P., Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide from the Gut Bacterium Ruminococcus gnavus E1, in Escherichia coli. Front. Microbiol. 2018, 9,1688.

Prof. Dr. Peter Neubauer
Technische Universität Berlin
Fachgebiet Bioverfahrenstechnik
Institut für Biotechnologie
TU Berlin
Ackerstrasse 76, ACK24
13355 Berlin
+49 (0)30-314-72269
+49 (0)30-314-27577

Publications (selection)

Hellendahl, K. F., Kaspar, F., Zhou, X., Yang, Z., Huang, Z., Neubauer, P., Kurreck, A. Optimized Biocatalytic Synthesis of 2-Selenopyrimidine Nucleosides by Transglycosylation. ChemBioChem. 2021, 22, 2002.

Kaspar, F., Neubauer, P., Kurreck, A. Kinetic Analysis of the Hydrolysis of Pentose-1-phosphates through Apparent Nucleoside Phosphorolysis Equilibrium Shifts*. ChemPhysChem2021, 22(3), 283-287.

Santolin, L., Waldburger, S., Neubauer, P., Riedel, S. L., Substrate-Flexible Two-Stage Fed-Batch Cultivations for the Production of the PHA Copolymer P(HB-co-HHx) With Cupriavidus necator Re2058/pCB113. Front. Bioeng. Biotechnol., 2021, 9, 623890.

Kaspar, F., Stone, M. R. L., Neubauer, P., Wagner, A., Route efficiency assessment and review of the synthesis of β-nucleosides via N-glycosylation of nucleobases. Green Chem., 2021, 23, 37-50.

Hans, S., Haby, B., Krausch, N., Barz, T., Neubauer, P., Cruz-Bournazou, M. N., Automated conditional screening of multiple Escherichia coli strains in parallel adaptive fed-batch cultivations. Bioengin., 2020, 7, 145.

Anane, E., Garcia, Á. C., Haby, B., Hans, S., Krausch, N., Krewinkel, M., Hauptmann, P., Neubauer, P., Cruz Bournazou, M.N., A model-based framework for parallel scale down fed-batch cultivations in mini-bioreactors for accelerated phenotyping. Biotechnol Bioeng., 2019, 116 (11), 2906-2918.

Marbà-Ardébol, A. M., Bockisch, A., Neubauer, P., Junne, S., Sterol synthesis and cell size distribution under oscillatory growth conditions in Saccharomyces cerevisiae scale-down cultivations. Yeast., 2018, 35(2), 213-223.

Cruz-Bournazou, M. N., Barz, T., Nickel, D., Glauche, F., Knepper, A., Neubauer, P., Online Optimal Experimental Re-Design in Robotic Parallel Fed-Batch Cultivation Facilities for Validation of Macro-Kinetic Growth Models at the Example of E. coli. Biotechnol Bioengin., 2017, 114(3), 610-619.

Latest News

UniSysCat group leader Peter Neubauer has won Agilent's Thought Leader Award, which is endowed with 1.9 million US Dollars. We asked him, how this award will impact his research in UniSysCat.