Research interests

  • Gene regulation
  • Bioprocess development
  • Regulatory small RNAs
  • Strain engineering

Research Units in UniSysCat

Dr. Matthias Gimpel
Technische Universität Berlin
Fachgebiet Bioverfahrenstechnik
Institut für Biotechnologie
Ackerstraße 76, ACK24
13355 Berlin
+49 (030) -314-79471


Publications (selection)

Fan, Q., Caserta, G., Lorent, C., Zebger, I., Neubauer, P., Lenz, O. & Gimpel, M. (2022) High-yield production of catalytically active regulatory [NiFe]-hydrogenase from Cupriavidus necator in Escherichia coli. Front Microbiol.

Fan, Q., Waldburger, S., Neubauer, P., Riedel, SL. & Gimpel, M. (2022) Implementation of a high cell density fed-batch for heterologous production of active [NiFe]-hydrogenase in Escherichia coli bioreactor cultivations. Microb Cell Fact. 21:193.

Gimpel, M. & Brantl, S. (2016). Dual-function sRNA encoded peptide SR1P modulates moonlight activity of B. subtilis GapA. RNA Biol.

Kaspar, F., Giessmann, R., Hellendahl, F., Neubauer, P. Wagner, A. & Gimpel, M. (2020) General principles for yield optimization of nucleoside phosphorylase-catalyzed transglycosylations. ChemBioChem.

Gimpel, M., Preis, H., Barth, E., Gramzow, L. & Brantl, S. (2012). SR1 – a small RNA with two remarkably conserved functions. Nucleic Acids Res. 40: 11659-11672

Gimpel, M. & Brantl, S. (2012). Construction of a modular plasmid family for chromosomal integration in Bacillus subtilis. J Microbiol Meth. 91: 312-317.

Fan, Q., Caserta, G., Lorent, C., Lenz, O., Neubauer, P. & Gimpel, M. (2021) Optimization of culture conditions for oxygen-tolerant regulatory [NiFe]-hydrogenase production from Ralstonia eutropha H16 in Escherichia coli. Microorganisms. 9: 1195.

Fan, Q., Neubauer, P. & Gimpel, M. (2021) Production of soluble regulatory hydrogenase from Ralstonia eutropha in Escherichia coli using a fed-batch-based autoinduction system. Microb Cell Fact. 20: 201.

Kaspar, F., Giessmann, R., Neubauer, P., Wagner, A. and Gimpel, M. (2019) Thermodynamic reaction control of nucleoside phosphorolysis. Advanced synthesis & catalysis

Gimpel, M., Maiwald, C., Wiedemann, C., Görlach, M. & Brantl, S. (2017). Characterization of the interaction between the small RNA-encoded peptide SR1P and GapA from Bacillus subtilis. Microbiology. 163: 1248-1259.