Understanding how drugs bind to their target is very helpful for drug development. UniSysCat researchers Sohraby and Nunes Alves reviewed the latest computational methods for predicting the kinetics of binding mechanisms.
UniSysCat researchers reveal a unique mechanism by which an NAD+-reducing [NiFe] hydrogenase becomes more oxygen tolerant, which is of interest for hydrogen energy strategies and regenerating nucleotide cofactors.
Neuroscientists are looking for accurate sensors to image nerve signals in tissue, particularly the brain. UniSysCat researchers now shed light on the voltage-sensing mechanism of the fluorescence of microbial rhodopsins.
An international team including UniSysCat researcher Nadia Elghobashi-Meinhardt elucidated the mechanism & inhibition of Wnt acylation mediated by the enzyme PORCN - a process comprising an important signalling pathway in our…
A research team around UniSysCat group leader Prof. Roldán Cuenya from FHI Berlin provides insights into size effects and structural changes important for the activity of cobalt oxide nanoparticles at work.
A team of UniSysCat researchers found a coupling scheme for the ATP-driven electron transfer in the double-cubane cluster protein and its associated metalloenzyme based on the structure of their complex.